Proteintech, 83707-2-RR, SCF Recombinant monoclonal antibody

Size: 20ul / 100ul The SCF (83707-2-RR) by Proteintech is a Recombinant antibody targeting SCF in WB, ELISA applications with reactivity to human, mouse, rat samples 83707-2-RR targets SCF in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: COLO 320 cells, PC-12 cells, Neuro-2a cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Stem cell factor (SCF) also known as mast cell growth factor, steel factor, and kit ligand, is a hematopoietic growth factor. SCF is a critical protein with key roles in the cell such as hematopoiesis, gametogenesis and melanogenesis. SCF activates multiple signal pathways by binding with c-kit receptor. SCF and its receptor, c-kit ligand (KL), are up-regulated in particular human malignancies including gastrointestinal stromal tumor (GISTs), breast cancer, hematopoietic cell, myeloid leukaemia, and glioma. The SCF/c-KIT system also plays a relevant role in cell fate decision, and its activity is widely known to control cell proliferation, differentiation, survival and apoptosis. SCF is a 35 to 45 kDa monomeric glycoprotein. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Fusion Protein Predict reactive species Full Name: KIT ligand Calculated Molecular Weight: 31kDa Observed Molecular Weight: 28 kDa, 45 kDa GenBank Accession Number: NM_021843.4 Gene Symbol: Kitlg Gene ID (NCBI): 60427 RRID: AB_3671309 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P21581-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.