Proteintech, 83774-1-RR, CALCA/Calcitonin Recombinant monoclonal antibody

Size: 20ul / 100ul The CALCA/Calcitonin (83774-1-RR) by Proteintech is a Recombinant antibody targeting CALCA/Calcitonin in IF/ICC, FC (Intra), ELISA applications with reactivity to human samples 83774-1-RR targets CALCA/Calcitonin in IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: TT cells Positive FC (Intra) detected in: TT cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800 Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information Calcitonin is a peptide hormone consisting of 32 amino acids, primarily synthesized by the parafollicular cells (C cells) of the human thyroid gland. It plays a crucial role in regulating calcium levels in the blood by decreasing them. Calcitonin opposes the actions of parathyroid hormone, which increases blood calcium levels. Calcitonin works through a G protein-coupled receptor, known as the calcitonin receptor, which predominantly transmits signals via the cAMP and PLC/IP3 pathways. Its primary physiological effects are on osteoclasts and the tubular epithelium of kidneys. Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg1060 Product name: Recombinant Human Procalcitonin/CALCA protein (His Tag) Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 26-141 aa of NM_001741.3 Sequence: APFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN Predict reactive species Full Name: Calcitonin Calculated Molecular Weight: 15kDa GenBank Accession Number: NM_001741.3 Gene Symbol: CALCA Gene ID (NCBI): 796 RRID: AB_3671370 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P01258 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.