Proteintech, 84149-4-RR, ARHGEF11 Recombinant monoclonal antibody

Size: 20ul / 100ul The ARHGEF11 (84149-4-RR) by Proteintech is a Recombinant antibody targeting ARHGEF11 in WB, ELISA applications with reactivity to human samples 84149-4-RR targets ARHGEF11 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HEK-293T cells, HuH-7 cells, COLO 205 cells, MDA-MB-453 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:16000 Background Information ARHGEF11 (Rho guanine nucleotide exchange factor 11) is a specific guanine nucleotide exchange factor (GEF) for RhoA, which is a critical regulator of actin cytoskeleton dynamics and organization of dendritic spines and inhibitor of spine maintenance (PMID: 28036092). ARHGEF11 has been proven to promote tumor metastasis in glioblastoma and ovarian carcinoma (PMID: 33122451). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag33104 Product name: Recombinant human ARHGEF11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1223-1522 aa of Sequence: ETQAAQEPEDDLTPTPSVISVTSHPWDPGSPGQAPPGGEGDNTQLAGLEGERPEQEDMGLCSLEHLPPRTRNSGIWESPELDRNLAEDASSTEAAGGYKVVRKAEVAGSKVVPALPESGQSEPGPPEVEGGTKATGNCFYVSMPSGPPDSSTDHSEAPMSPPQPDSLPAGQTEPQPQLQGGNDDPRRPSRSPPSLALRDVGMIFHTIEQLTLKLNRLKDMELAHRELLKSLGGESSGGTTPVGSFHTEAARWTDGSLSPPAKEPLASDSRNSHELGPCPEDGSDAPLEDSTADAAASPGP Predict reactive species Full Name: Rho guanine nucleotide exchange factor (GEF) 11 Calculated Molecular Weight: 168 kDa Observed Molecular Weight: 220 kDa Gene Symbol: ARHGEF11 Gene ID (NCBI): 9826 RRID: AB_3671714 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O15085 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.