Proteintech, 84421-3-RR, ACVRL1 Recombinant monoclonal antibody

Size: 20ul / 100ul The ACVRL1 (84421-3-RR) by Proteintech is a Recombinant antibody targeting ACVRL1 in WB, ELISA applications with reactivity to human samples 84421-3-RR targets ACVRL1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HUVEC cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information ACVRL1 (ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: FusionProtein Predict reactive species Full Name: activin A receptor type II-like 1 Calculated Molecular Weight: 56 kDa Observed Molecular Weight: 63 kDa GenBank Accession Number: BC042637 Gene Symbol: ACVRL1 Gene ID (NCBI): 94 RRID: AB_3671949 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P37023 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.