Proteintech, 84455-2-RR, CD70 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD70 (84455-2-RR) by Proteintech is a Recombinant antibody targeting CD70 in IF/ICC, ELISA applications with reactivity to human samples 84455-2-RR targets CD70 in IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: THP-1 cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information CD70, also known as tumor necrosis factor ligand superfamily member 7 (TNFSF7) or CD27 ligand (CD27L), is a transmembrane protein that plays a significant role in the immune system. It is the unique ligand for CD27, a member of the tumor necrosis factor receptor (TNFR) family, and is transiently upregulated upon stimulation of immune cells. CD70 is expressed on lymphocytes and dendritic cells, and its expression can be regulated by activation signals received via toll-like receptors (TLRs), CD40, and the antigen receptor MHC II. It provides complex and not completely understood signaling for B cell development. CD70 is also expressed on various solid tumors and hematolymphoid malignancies, where it may contribute to a poor prognosis. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD70 molecule Calculated Molecular Weight: 21 kDa GenBank Accession Number: BC000725 Gene Symbol: CD70 Gene ID (NCBI): 970 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P32970 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.