Proteintech, 84458-4-RR, P2RX6 Recombinant monoclonal antibody

Size: 20ul / 100ul The P2RX6 (84458-4-RR) by Proteintech is a Recombinant antibody targeting P2RX6 in WB, ELISA applications with reactivity to human, mouse samples 84458-4-RR targets P2RX6 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse skeletal muscle tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information The P2 receptors have two subfamilies in mammalian cells, P2X and P2Y. P2X family of ligand-gated ion channel receptors have seven members, P2RX1-7, which all constitute non-selective cation channels proposed to be functional under a homo- or heterotrimeric association. P2RX6 is predominantly expressed in skeletal muscle, and regulated by p53. It's reported that ATP might increase renal cell carcinoma cells migration and invasion through P2RX6.(PMID: 31159832, PMID:9242461) Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag12331 Product name: Recombinant human P2RX6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-330 aa of BC033488 Sequence: MGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVT Predict reactive species Full Name: purinergic receptor P2X, ligand-gated ion channel, 6 Calculated Molecular Weight: 431 aa, 48 kDa Observed Molecular Weight: 45 kDa GenBank Accession Number: BC033488 Gene Symbol: P2RX6 Gene ID (NCBI): 9127 RRID: AB_3671983 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: O15547 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.