Proteintech, 84481-4-RR, M-CSF Recombinant monoclonal antibody

Size: 20ul / 100ul The M-CSF (84481-4-RR) by Proteintech is a Recombinant antibody targeting M-CSF in WB, ELISA applications with reactivity to human samples 84481-4-RR targets M-CSF in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Jurkat cells, K-562 cells, THP-1 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information M-CSF plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration and plays a role in lipoprotein clearance (PMID: 29734839; 29679908; 28202039) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: colony stimulating factor 1 (macrophage) Calculated Molecular Weight: 60 kDa Observed Molecular Weight: 60 kDa GenBank Accession Number: BC021117 Gene Symbol: M-CSF Gene ID (NCBI): 1435 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P09603 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.