Proteintech, 84518-3-RR, CD64 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD64 (84518-3-RR) by Proteintech is a Recombinant antibody targeting CD64 in WB, IF/ICC, ELISA applications with reactivity to mouse samples 84518-3-RR targets CD64 in WB, IF/ICC, ELISA applications and shows reactivity with mouse samples. Tested Applications Positive WB detected in: RAW 264.7 cells, J774A.1 cells Positive IF/ICC detected in: RAW 264.7 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)/ICC: IF/ICC : 1:250-1:1000 Background Information Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: Fc receptor, IgG, high affinity I Calculated Molecular Weight: 45 kDa Observed Molecular Weight: 68-72 kDa GenBank Accession Number: NM_010186.5 Gene Symbol: Fcgr1 Gene ID (NCBI): 14129 RRID: AB_3672025 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P26151 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.