Proteintech, 84694-1-RR, Jagged1/CD339 Recombinant monoclonal antibody

Size: 20ul / 100ul The Jagged1/CD339 (84694-1-RR) by Proteintech is a Recombinant antibody targeting Jagged1/CD339 in WB, IF/ICC, ELISA applications with reactivity to human samples 84694-1-RR targets Jagged1/CD339 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HepG2 cells Positive IF/ICC detected in: IM-9 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800 Background Information Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: jagged 1 (Alagille syndrome) Calculated Molecular Weight: 1218 aa, 134 kDa Observed Molecular Weight: 150 kDa GenBank Accession Number: BC098393 Gene Symbol: Jagged1 Gene ID (NCBI): 182 RRID: AB_3672110 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P78504 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.