Proteintech, 85101-1-RR, ITPR1-Specific Recombinant monoclonal antibody

Size: 20ul / 100ul The ITPR1-Specific (85101-1-RR) by Proteintech is a Recombinant antibody targeting ITPR1-Specific in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples 85101-1-RR targets ITPR1-Specific in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: SH-SY5Y cells, HeLa cells, L02 cells, mouse brain tissue, rat brain tissue Positive IHC detected in: mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunohistochemistry (IHC): IHC : 1:200-1:800 Background Information ITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. It is a receptor for inositol 1,4,5-trisphosphate which is a second messenger that mediates the release of intracellular calcium. Defects in ITPR1 are the cause of spinocerebellar ataxia type 15 (SCA15). The antibody has no cross reaction with ITPR2 and ITPR3. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: inositol 1,4,5-triphosphate receptor, type 1 Calculated Molecular Weight: 314 kDa Observed Molecular Weight: 290-300 kDa GenBank Accession Number: NM_001099952 Gene Symbol: ITPR1 Gene ID (NCBI): 3708 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q14643 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.