Product Description
Size: 20ul / 100ul
The Stanniocalcin 2 (85910-1-RR) by Proteintech is a Recombinant antibody targeting Stanniocalcin 2 in WB, ELISA applications with reactivity to human samples
85910-1-RR targets Stanniocalcin 2 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HCT 116 cells, T-47D cells, HeLa cells, HepG2 cells, MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Background Information
Stanniocalcin (STC) is a family of secreted glycoprotein hormones that originally discovered in the corpuscles of Stannius, an endocrine gland of fish. STC1 and STC2, two homologues of STC family, are reported to involve in calcium and phosphate homeostasis. It is expressed in a wide variety of tissues such as kidney, spleen, heart, and pancreas. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. STC2 overexpression could promote tumor cell proliferation, invasion and metastasis in prostate cancer, ovarian cancer or neuroblastoma. STC2 is also vital for cytoprotective properties when exposed to ER stress and hypoxia.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg3119 Product name: Recombinant Human Stanniocalcin 2 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 25-302 aa of NM_003714.3 Sequence: TDATNPPEGPQDRSSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVSQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR Predict reactive species
Full Name: stanniocalcin 2
Calculated Molecular Weight: 33 kDa
Observed Molecular Weight: 33-35 kDa
GenBank Accession Number: NM_003714.3
Gene Symbol: Stanniocalcin 2
Gene ID (NCBI): 8614
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: O76061
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
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