Proteintech, 85927-1-RR, MYSM1-Specific Recombinant monoclonal antibody

Size: 20ul / 100ul The MYSM1-Specific (85927-1-RR) by Proteintech is a Recombinant antibody targeting MYSM1-Specific in WB, ELISA applications with reactivity to human, mouse samples 85927-1-RR targets MYSM1-Specific in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HeLa cells, NIH/3T3 cells, HEK-293 cells, HepG2 cells, A549 cells, RAW 264.7 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information MYSM1, also named as KIAA1915, belongs to the peptidase M67A family and MYSM1 subfamily. MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. It catalyzes the reaction: Ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol. MYSM1 is a marker of cancer. The antibody is specific to MYSM1. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: Myb-like, SWIRM and MPN domains 1 Calculated Molecular Weight: 95 kDa Observed Molecular Weight: 81 kDa GenBank Accession Number: NM_001085487 Gene Symbol: MYSM1 Gene ID (NCBI): 114803 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q5VVJ2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.