Proteintech, 86633-2-RR, CLEC5A Recombinant monoclonal antibody

Size: 20ul / 100ul The CLEC5A (86633-2-RR) by Proteintech is a Recombinant antibody targeting CLEC5A in WB, ELISA applications with reactivity to human samples 86633-2-RR targets CLEC5A in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: U-251 cells, U-87 MG cells, THP-1 cells, K-562 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information C-type lectin domain family 5 member A (CLEC5A, also known as CLECSF5 and MDL1) is a spleen tyrosine kinase (Syk)-coupled receptor abundantly expressed by monocytes, macrophages and neutrophils (PMID: 10449773). It has a pivotal function in activating multiple aspects of innate immunity against bacterial invasion (PMID: 28824166). Both in vitro and in vivo evidence supported that CLEC5A was involved in glioblastoma pathogenesis via regulation of PI3K/Akt pathway (PMID: 30834619). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: DNA Predict reactive species Full Name: C-type lectin domain family 5, member A Calculated Molecular Weight: 188 aa, 22 kDa Observed Molecular Weight: 22 kDa GenBank Accession Number: BC112099 Gene Symbol: CLEC5A Gene ID (NCBI): 23601 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9NY25 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.