Proteintech, 87015-1-RR, GALR2 Recombinant monoclonal antibody

Size: 20ul / 100ul The GALR2 (87015-1-RR) by Proteintech is a Recombinant antibody targeting GALR2 in WB, ELISA applications with reactivity to human, mouse, rat samples 87015-1-RR targets GALR2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HEK-293 cells, SH-SY5Y cells, C6 cells, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Galanin receptor type 2 (GALR2) is a receptor for galanin, GALP, and the hormone SPX1 (PMID:24517231). It is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamo-pituitary axis. Activation of the GALR2 may protect the hippocampus from neuronal damage (PMID: 17263796). It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibits adenylyl cyclase. GALR2 has a calculated molecular weight of 42 kDa. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag24154 Product name: Recombinant human GALR2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 287-387 aa of BC074915 Sequence: VNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA Predict reactive species Full Name: galanin receptor 2 Calculated Molecular Weight: 387 aa, 42 kDa Observed Molecular Weight: 42 kDa GenBank Accession Number: BC074915 Gene Symbol: GALR2 Gene ID (NCBI): 8811 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O43603 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.