Product Description
Size: 20ul / 100ul
The PPP6C (87155-1-RR) by Proteintech is a Recombinant antibody targeting PPP6C in WB, ELISA applications with reactivity to human, mouse, rat samples
87155-1-RR targets PPP6C in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: HeLa cells, HepG2 cells, HEK-293T cells, Jurkat cells, NIH/3T3 cells, mouse testis tissue, rat testis tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
PPP6C (Protein Phosphatase 6 Catalytic Subunit or simply PP6) is a highly conserved serine/threonine phosphatase belonging to the PP2A-like subfamily. This enzyme complex plays critical roles in a wide array of fundamental cellular processes, including cell cycle progression, DNA damage response, NF-κB signaling, and microtubule organization. PPP6C mutations are found across multiple cancer types but are most common in melanoma and other skin cancers (PMID: 33789117).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag8554 Product name: Recombinant human PPP6C protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-305 aa of BC006990 Sequence: MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL Predict reactive species
Full Name: protein phosphatase 6, catalytic subunit
Calculated Molecular Weight: 305 aa, 35 kDa
Observed Molecular Weight: 30-35 kDa
GenBank Accession Number: BC006990
Gene Symbol: PPP6C
Gene ID (NCBI): 5537
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: O00743
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
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