Proteintech, 87294-1-RR, Phospho-ITPR1 (Ser1764) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-ITPR1 (Ser1764) (87294-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-ITPR1 (Ser1764) in WB, ELISA applications with reactivity to human, mouse, rat samples 87294-1-RR targets Phospho-ITPR1 (Ser1764) in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information ITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. Phospho-ITPR1 (Thr853) is a phosphorylated form of the inositol-trisphosphate receptor type 1 (ITPR1) protein at threonine residue 853. This phosphorylation site is involved in the regulation of calcium signaling pathways within cells. The specific function and role of Thr853 phosphorylation in ITPR1's activity are not detailed in the provided resources, but phosphorylation events on ITPR1 are known to influence its function, which affects calcium release from the endoplasmic reticulum. Calcium signaling is critical for various cellular processes, including muscle contraction, neurotransmitter release, and cellular division. This antibody is equivalent to Ser1756 in rat. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: inositol 1,4,5-triphosphate receptor, type 1 Calculated Molecular Weight: 314 kDa Observed Molecular Weight: 320 kDa GenBank Accession Number: NM_001378452 Gene Symbol: ITPR1 Gene ID (NCBI): 3708 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q14643 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.