Product Description
Size: 20ul / 100ul
The CD18 (87481-2-RR) by Proteintech is a Recombinant antibody targeting CD18 in WB, ELISA applications with reactivity to mouse samples
87481-2-RR targets CD18 in WB, ELISA applications and shows reactivity with mouse samples.
Tested Applications
Positive WB detected in: A20 cells, RAW 264.7 cells, mouse spleen tissue, mouse thymus tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during the immune response, and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).
Specification
Tested Reactivity: mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg10459 Product name: Recombinant mouse ITB2 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011456 of Sequence: \ Predict reactive species
Full Name: integrin beta 2
Observed Molecular Weight: 85-90 kDa
Gene Symbol: CD18
Gene ID (NCBI): 16414
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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