Proteintech, 87482-1-RR, ITB6 Recombinant monoclonal antibody

Size: 20ul / 100ul The ITB6 (87482-1-RR) by Proteintech is a Recombinant antibody targeting ITB6 in WB, ELISA applications with reactivity to human, mouse, rat samples 87482-1-RR targets ITB6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: A431 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Mouse Itgb6 (integrin β6) protein is a member of the integrin family and binds with the αv subunit to form the transmembrane receptor αvβ6. It mediates cell adhesion and migration by recognizing the RGD sequence in the extracellular matrix (such as fibronectin and laminin). The core function of Itgb6 is to act as a key activator of transforming growth factor-β (TGF-β), playing an important role in tissue damage repair, fibrosis, and tumorigenesis. In various mouse tumor models, including pancreatic cancer and skin cancer, high expression of Itgb6 promotes tumor invasion and metastasis, making it an important tumor biomarker and therapeutic target. Its signaling involves pathways such as FAK/PI3K, regulating cell survival and epithelial-mesenchymal transition (EMT). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10455 Product name: Recombinant mouse ITB6 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011460 of Sequence: \ Predict reactive species Full Name: integrin beta 6 Observed Molecular Weight: 100 kDa Gene Symbol: Itgb6 Gene ID (NCBI): 16420 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.