Proteintech, 87539-1-RR, Integrin apha V Recombinant monoclonal antibody

Size: 20ul / 100ul The Integrin apha V (87539-1-RR) by Proteintech is a Recombinant antibody targeting Integrin apha V in WB, ELISA applications with reactivity to mouse, rat samples 87539-1-RR targets Integrin apha V in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: NIH/3T3 cells, C6 cells, mouse kidney tissue, rat kidney tissue, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha V, also known as CD51, is a type I transmembrane glycoprotein composed of an extracellular domain, a transmembrane region, and a cytoplasmic domain (PMID: 2430295; 1690718). It can form heterodimers with one of the five beta integrin subunits (beta 1, 3, 5, 6, 8) that recognize ligands containing the sequence Arg-Gly-Asp, such as vitronectin, fibronectin, and osteopontin (PMID: 37087799). Integrin alpha V mainly plays a role in extracellular matrix-mediated cell adhesion and migration, differentiation, wound healing, inflammation, tumorigenesis, proliferation, angiogenesis, and metastasis. Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10462 Product name: Recombinant mouse ITAV protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011453 of Sequence: \ Predict reactive species Full Name: integrin alpha V Observed Molecular Weight: 120 kDa Gene Symbol: Itgav Gene ID (NCBI): 16410 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P43406 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.