Proteintech, 98097-1-RR, Anti-Human ICAM3/CD50 Rabbit Recombinant Antibody

Size: 100ug The ICAM3/CD50 (98097-1-RR) by Proteintech is a Recombinant antibody targeting ICAM3/CD50 in FC applications with reactivity to human samples 98097-1-RR targets ICAM3/CD50 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information The intercellular adhesion molecule (ICAM) family is a subfamily of immunoglobulin superfamily with five known ICAM family members (ICAM1 to ICAM5) which play a role in inflammation, immune responses, and intracellular signaling (PMID: 23287428; 29477378). ICAM3, also known as CD50, is a type I transmembrane glycoprotein that contains five C2-type immunoglobulin-like domains in its extracellular region, a single transmembrane segment, and a C-terminus cytoplasmic tail. ICAM3 is selectively expressed on leukocytes (PMID: 1730916; 8132828). It is the primary ligand for LFA-1 and is involved in various immune processes, including T-cell activation, and macrophage recognition of apoptotic cells (PMID: 11812993; 23775590). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: intercellular adhesion molecule 3 Calculated Molecular Weight: 547 aa, 60 kDa GenBank Accession Number: BC058903 Gene Symbol: ICAM3/CD50 Gene ID (NCBI): 3385 RRID: AB_3672244 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P32942 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.