Proteintech, 98103-1-RR, Anti-Human CD8b Rabbit Recombinant Antibody

Size: 100ug The CD8b (98103-1-RR) by Proteintech is a Recombinant antibody targeting CD8b in FC applications with reactivity to human samples 98103-1-RR targets CD8b in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on the surface of cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: CD8b molecule Calculated Molecular Weight: 243 aa, 27 kDa GenBank Accession Number: BC100913 Gene Symbol: CD8B Gene ID (NCBI): 926 RRID: AB_3672250 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P10966 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.