Proteintech, 98309-8-MR, Anti-Rabbit CD27 Mouse Recombinant Antibody

Size: 100ug The CD27 (98309-8-MR) by Proteintech is a Recombinant antibody targeting CD27 in FC applications with reactivity to rabbit samples 98309-8-MR targets CD27 in FC applications and shows reactivity with rabbit samples. Tested Applications Positive FC detected in: rabbit splenocytes cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1. Specification Tested Reactivity: rabbit Host / Isotype: Mouse / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2485 Product name: recombinant rabbit CD27 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 10007020 of Sequence: Predict reactive species Full Name: CD27 Gene Symbol: CD27 Gene ID (NCBI): 100346881 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.