Proteintech, 98351-1-MR, Anti-Rabbit CD19 Mouse Recombinant Antibody

Size: 100ug The CD19 (98351-1-MR) by Proteintech is a Recombinant antibody targeting CD19 in FC applications with reactivity to rabbit samples 98351-1-MR targets CD19 in FC applications and shows reactivity with rabbit samples. Tested Applications Positive FC detected in: rabbit splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908). Specification Tested Reactivity: rabbit Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: CatNo: Eg3526 Product name: recombinant rabbit CD19-mFc protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 10007198 of Sequence: / Predict reactive species Full Name: CD19 Gene Symbol: CD19 Gene ID (NCBI): 100345233 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.