Proteintech, 98355-2-RR, Anti-Human CD40L/CD154 Rabbit Recombinant Antibody

Size: 100ug The CD40L/CD154 (98355-2-RR) by Proteintech is a Recombinant antibody targeting CD40L/CD154 in FC applications with reactivity to human samples 98355-2-RR targets CD40L/CD154 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: PMA and ionomycin treated human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33 kDa transmembrane homologue or 18 kDa soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and on a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD40 ligand Calculated Molecular Weight: 261 aa, 29 kDa GenBank Accession Number: BC071754 Gene Symbol: CD40 Ligand Gene ID (NCBI): 959 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P29965 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.