Proteintech, 98357-1-RR, Anti-Mouse CLEC12A/CD371 Rabbit Recombinant Antibody

Size: 100ug The CLEC12A/CD371 (98357-1-RR) by Proteintech is a Recombinant antibody targeting CLEC12A/CD371 in FC applications with reactivity to mouse samples 98357-1-RR targets CLEC12A/CD371 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CLEC12A, also known as CD371, MICL, DCAL-2 or CLL-1, is a type II transmembrane glycoprotein and a member of the C-type lectin superfamily (PMID: 30401586). This protein, which contains a single C-type lectin-like domain and a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), is related to LOX-1 and Dectin-1 and is variably spliced and highly N-glycosylated (PMID: 14739280). Its ITIM sequence recruits the tyrosine phosphatases SHP-1 and SHP-2 to negatively regulate Syk signaling. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2726 Product name: Recombinant Mouse CLEC12A protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 65-267 aa of / Sequence: YTTLATEMIKSNQLQRAKEELQENVFLQLKHNLNSSKKIKNLSAMLQSTATQLCRELYSKEPEHKCKPCPKGSEWYKDSCYSQLNQYGTWQESVMACSARNASLLKVKNKDVLEFIKYKKLRYFWLALLPRKDRTQYPLSEKMFLSEESERSTDDIDKKYCGYIDRVNVYYTYCTDENNIICEETASKVQLESVLNGLPEDSR Predict reactive species Full Name: C-type lectin domain family 12, member a Calculated Molecular Weight: 31 kDa GenBank Accession Number: / Gene Symbol: Clec12a Gene ID (NCBI): 232413 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q504P2 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.