Proteintech, 98433-3-RR, Anti-Mouse CD38 Rabbit Recombinant Antibody

Size: 100ug The CD38 (98433-3-RR) by Proteintech is a Recombinant antibody targeting CD38 in FC applications with reactivity to mouse samples 98433-3-RR targets CD38 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: C57BL/6 mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2915 Product name: Recombinant Mouse CD38 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 45-304 aa of NM_007646.5 Sequence: LRPRSLLVWTGEPTTKHFSDIFLGRCLIYTQILRPEMRDQNCQEILSTFKGAFVSKNPCNITREDYAPLVKLVTQTIPCNKTLFWSKSKHLAHQYTWIQGKMFTLEDTLLGYIADDLRWCGDPSTSDMNYVSCPHWSENCPNNPITVFWKVISQKFAEDACGVVQVMLNGSLREPFYKNSTFGSVEVFSLDPNKVHKLQAWVMHDIEGASSNACSSSSLNELKMIVQKRNMIFACVDNYRPARFLQCVKNPEHPSCRLNT Predict reactive species Full Name: CD38 antigen Calculated Molecular Weight: 34 kDa GenBank Accession Number: NM_007646.5 Gene Symbol: Cd38 Gene ID (NCBI): 12494 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P56528 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.