Proteintech, 98527-1-RR, Anti-Human TCR Vγ5Vδ1 Rabbit Recombinant Antibody

Size: 100ug The TCR Vγ5Vδ1 (98527-1-RR) by Proteintech is a Recombinant antibody targeting TCR Vγ5Vδ1 in FC applications with reactivity to human samples 98527-1-RR targets TCR Vγ5Vδ1 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information TCR Vγ5Vδ1 refers to a specific type of T cell receptor (TCR) found on γδ T cells. These cells are a distinct subset of T lymphocytes that play a role in immune responses, particularly in maintaining tissue integrity and responding to stress signals. The Vγ5Vδ1 TCR is uniquely expressed on a population of T cells called dendritic epidermal T cells (DETCs) that reside in the epidermis (PMID: 35260830, 35031803). The Vγ5Vδ1 TCR-CD3 complex forms an asymmetric dimer, with the Vγ5 domains of each protomer interacting to create a back-to-back structure. This dimeric form is essential for T cell activation (PMID: 38657677). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: TCR Vγ5Vδ1 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.