Proteintech, 98532-2-RR, Anti-Mouse IL-17RA Rabbit Recombinant Antibody

Size: 100ug The IL-17RA (98532-2-RR) by Proteintech is a Recombinant antibody targeting IL-17RA in FC applications with reactivity to mouse samples 98532-2-RR targets IL-17RA in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse bone marrow cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information IL-17 is a proinflammatory cytokine. IL-17 can signal as homodimers or heterodimers through a heterodimeric receptor formed by IL-17 receptor A (IL-17RA) and IL-17 receptor C (IL-17RC) subunits. IL-17RA is ubiquitously expressed in both the epithelial and hematopoietic cell compartments. IL-17/IL-17RA signaling plays an important physiological role in regulating the mucosal host defense against invading microorganisms, but it can also play pathogenic roles in several inflammatory or autoimmune conditions; furthermore, it has been described as pro-tumorigenic in several cancer types. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2584 Product name: recombinant mouse IL-17RA/IL-17R protein Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 32-322 aa of NM_008359.2 Sequence: SPRLLDFPAPVCAQEGLSCRVKNSTCLDDSWIHPKNLTPSSPKNIYINLSVSSTQHGELVPVLHVEWTLQTDASILYLEGAELSVLQLNTNERLCVKFQFLSMLQHHRKRWRFSFSHFVVDPGQEYEVTVHHLPKPIPDGDPNHKSKIIFVPDCEDSKMKMTTSCVSSGSLWDPNITVETLDTQHLRVDFTLWNESTPYQVLLESFSDSENHSCFDVVKQIFAPRQEEFHQRANVTFTLSKFHWCCHHHVQVQPFFSSCLNDCLRHAVTVPCPVISNTTVPKPVADYIPLW Predict reactive species Full Name: interleukin 17 receptor A Calculated Molecular Weight: 98kDa GenBank Accession Number: NM_008359.2 Gene Symbol: Il17ra Gene ID (NCBI): 16172 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q60943 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.