Proteintech, 98556-1-RR, Anti-Mouse IL-17C Rabbit Recombinant Antibody

Size: 100ug The IL-17C (98556-1-RR) by Proteintech is a Recombinant antibody targeting IL-17C in FC (Intra) applications with reactivity to mouse samples 98556-1-RR targets IL-17C in FC (Intra) applications and shows reactivity with mouse samples. Tested Applications Positive FC (Intra) detected in: Transfected HEK-293T cells Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information IL-17C is a member of the IL-17 cytokine family, was cloned from a human fetal kidney library in 2000 (PMID: 10639155). The IL-17 family comprises at least 6 proinflammatory cytokines that share a conserved cystine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins that induce local cytokine production and recruit granulocytes to sites of inflammation (PMID: 15485625; 11574464). IL-17C is selectively induced in epithelia by bacterial challenge and inflammatory stimuli (PMID: 21993848). IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection (PMID: 21993849). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2840 Product name: recombinant mouse Il17c protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 15-194 aa of NM_145834.3 Sequence: HQDPPSWGKPRSHRTLRCYSAEELSHGQAPPHLLTRSARWEQALPVALVASLEATGHRRQHEGPLAGTQCPVLRPEEVLEADTHERSISPWRYRIDTDENRYPQKLAVAECLCRGCINAKTGRETAALNSVQLLQSLLVLRRQPCSRDGTADPTPGSFAFHTEFIRVPVGCTCVLPRSTQ Predict reactive species Full Name: interleukin 17C Calculated Molecular Weight: 22 kDa GenBank Accession Number: NM_145834.3 Gene Symbol: Il17c Gene ID (NCBI): 234836 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q8K4C5 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.