Proteintech, 98751-1-MR, Anti-Human CD64 Mouse Recombinant Antibody

Size: 100ug The CD64 (98751-1-MR) by Proteintech is a Recombinant antibody targeting CD64 in FC applications with reactivity to human samples 98751-1-MR targets CD64 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses. The calculated molecular weight of CD64 is 43 kDa, while the glycosylated CD64 has a higher apparent molecular weight. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: unknow Predict reactive species Full Name: Fc fragment of IgG, high affinity Ia, receptor (CD64) Gene Symbol: FCGR1A Gene ID (NCBI): 2209 ENSEMBL Gene ID: ENSG00000150337 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P12314 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.