Proteintech, APC-65062, APC Anti-Mouse CD40 (1C10)

Size: 100ug The CD40 (APC-65062) by Proteintech is a Monoclonal antibody targeting CD40 in FC applications with reactivity to mouse samples APC-65062 targets CD40 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497). Specification Tested Reactivity: mouse Cited Reactivity: mouse Host / Isotype: Rat / IgG2a, kappa Class: Monoclonal Type: Antibody Immunogen: sCD40 Predict reactive species Full Name: CD40 antigen GenBank Accession Number: BC029254 Gene Symbol: Cd40 Gene ID (NCBI): 21939 RRID: AB_2882964 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Affinity purification UNIPROT ID: P27512 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.