Proteintech, APC-FcA65572, FcZero-rAb™ APC Anti-Human CD64 (10.1) Rabbit Recombinant Antibody

Size: 100tests The CD64 (APC-FcA65572) by Proteintech is a Recombinant antibody targeting CD64 in FC applications with reactivity to human, monkey, non-human primates samples APC-FcA65572 targets CD64 in FC applications and shows reactivity with human, monkey, non-human primates samples. Tested Applications Positive FC detected in: human PBMCs, cynomolgus PBMCs Recommended dilution Flow Cytometry (FC): FC : 5 ul per 10^6 cells in 100 μl suspension Background Information Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses. Specification Tested Reactivity: human, monkey, non-human primates Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Human rheumatoid synovial fluid cells and fibronectin-purified monocytes. Predict reactive species Full Name: Fc fragment of IgG, high affinity Ia, receptor (CD64) Calculated Molecular Weight: 374 aa, 43 kDa GenBank Accession Number: BC032634 Gene Symbol: FCGR1A Gene ID (NCBI): 2209 ENSEMBL Gene ID: ENSG00000150337 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Excitation Laser: Red Laser (633 nm) Form: Liquid Purification Method: Protein A purification UNIPROT ID: P12314 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.