Proteintech, APC-FcA65672, FcZero-rAb™ APC Anti-Mouse CD11b (M1/70) Rabbit IgG Recombinant Antibody

Size: 100ug The CD11b (APC-FcA65672) by Proteintech is a Recombinant antibody targeting CD11b in FC applications with reactivity to human, mouse, rabbit, monkey, guinea pig, non-human primates samples APC-FcA65672 targets CD11b in FC applications and shows reactivity with human, mouse, rabbit, monkey, guinea pig, non-human primates samples. Tested Applications Positive FC detected in: mouse bone marrow cells, guinea pig splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.1 ug per 10^6 cells in a 100 µl suspension Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). Specification Tested Reactivity: human, mouse, rabbit, monkey, guinea pig, non-human primates Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: integrin alpha M Calculated Molecular Weight: 127 kDa GenBank Accession Number: BC156991 Gene Symbol: CD11b Gene ID (NCBI): 16409 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Excitation Laser: Red Laser (633 nm) Form: Liquid Purification Method: Protein A purification UNIPROT ID: E9Q604 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.