Proteintech, APC-FcA98017, FcZero-rAb™ APC Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody

Size: 100tests The B7-H3/CD276 (APC-FcA98017) by Proteintech is a Recombinant antibody targeting B7-H3/CD276 in FC applications with reactivity to human samples APC-FcA98017 targets B7-H3/CD276 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human monocyte-derived immature dendritic cells Recommended dilution Flow Cytometry (FC): FC : 5 ul per 10^6 cells in 100 μl suspension Background Information B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD276 molecule Calculated Molecular Weight: 57 kDa GenBank Accession Number: NM_001024736 Gene Symbol: CD276 Gene ID (NCBI): 80381 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Excitation Laser: Red Laser (633 nm) Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q5ZPR3 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.