Proteintech, APC-FcA98031, FcZero-rAb™ APC Anti-Mouse CD206 Rabbit Recombinant Antibody

Size: 100ug The CD206 (APC-FcA98031) by Proteintech is a Recombinant antibody targeting CD206 in FC applications with reactivity to mouse samples APC-FcA98031 targets CD206 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse peritoneal macrophages Recommended dilution Flow Cytometry (FC): FC : 0.1 ug per 10^6 cells in 100 μl suspension Background Information CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: mannose receptor, C type 1 Calculated Molecular Weight: 165 kDa GenBank Accession Number: NM_008625.2 Gene Symbol: CD206 Gene ID (NCBI): 17533 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q2HZ94 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.