Proteintech, APC-FcA98046, FcZero-rAb™ APC Anti-Rat IL-2 Rabbit Recombinant Antibody

Size: 100ug The IL-2 (APC-FcA98046) by Proteintech is a Recombinant antibody targeting IL-2 in FC (Intra) applications with reactivity to rat samples APC-FcA98046 targets IL-2 in FC (Intra) applications and shows reactivity with rat samples. Tested Applications Positive FC (Intra) detected in: PMA and ionomycin treated rat splenocytes Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.1 ug per 10^6 cells in 100 μl suspension Background Information Interleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641). Specification Tested Reactivity: rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg0260 Product name: Recombinant Rat IL-2 protein (His Tag) Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 21-155 aa of NM_053836 Sequence: MAPTSSPAKETQQHLEQLLLDLQVLLRGIDNYKNLKLPMMLTFKFYLPKQATELKHLQCLENELGALQRVLDLTQSKSFHLEDAGNFISNIRVTVVKLKGSENKFECQFDDEPATVVEFLRRWIAICQSIISTMTQ Predict reactive species Full Name: interleukin 2 Calculated Molecular Weight: 18 kDa GenBank Accession Number: NM_053836 Gene Symbol: Il2 Gene ID (NCBI): 116562 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: P17108 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.