Proteintech, APC-FcA98106, FcZero-rAb™ APC Anti-Human FLT3/CD135 Rabbit Recombinant Antibody

Size: 100tests The FLT3/CD135 (APC-FcA98106) by Proteintech is a Recombinant antibody targeting FLT3/CD135 in FC applications with reactivity to human samples APC-FcA98106 targets FLT3/CD135 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: Reh cells Recommended dilution Flow Cytometry (FC): FC : 5 ul per 10^6 cells in 100 μl suspension Background Information FLT3 (also known as CD135 or FLK2) is a tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and of dendritic cells. FLT3 was originally identified by its expression in hematopoietic stem/progenitor cells (PMID: 7507245). It is important for the normal development of hematopoietic stem/progenitor cells. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: fms-related tyrosine kinase 3 Calculated Molecular Weight: 993 aa, 113 kDa GenBank Accession Number: BC036028 Gene Symbol: FLT3 Gene ID (NCBI): 2322 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: P36888 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.