Product Description
Size: 100tests
The SIRP beta 1/CD172b (APC-FcA98267) by Proteintech is a Recombinant antibody targeting SIRP beta 1/CD172b in FC applications with reactivity to human samples
APC-FcA98267 targets SIRP beta 1/CD172b in FC applications and shows reactivity with human samples.
Tested Applications
Positive FC detected in: human peripheral blood leukocytes
Recommended dilution
Flow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension
Background Information
SIRP beta 1, also known as CD172b, is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRP family members are cell surface signaling receptors differentially expressed in leukocytes and the central nervous system. SIRP beta 1 interacts with TYROBP/DAP12, a protein-bearing immunoreceptor tyrosine-based activation motif. SIRP beta 1 also participates in the recruitment of tyrosine kinase SYK.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg1668 Product name: Recombinant Human SIRP beta 1/CD172b protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 30-371 aa of NM_006065.5 Sequence: EDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEAALAPTAPL Predict reactive species
Full Name: signal-regulatory protein beta 1
Calculated Molecular Weight: 43kDa
GenBank Accession Number: NM_006065.5
Gene Symbol: SIRPB1
Gene ID (NCBI): 10326
Conjugate: APC Fluorescent Dye
Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: O00241-1
Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
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Collaboration
Tony Tang
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