Product Description
Size: 100ug
The IL-1R2 (APC-FcA98347) by Proteintech is a Recombinant antibody targeting IL-1R2 in FC applications with reactivity to mouse samples
APC-FcA98347 targets IL-1R2 in FC applications and shows reactivity with mouse samples.
Tested Applications
Positive FC detected in: mouse bone marrow cells
Recommended dilution
Flow Cytometry (FC): FC : 0.1 ug per 10^6 cells in a 100 µl suspension
Background Information
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.
Specification
Tested Reactivity: mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg2956 Product name: Recombinant Mouse IL-1R2 protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 14-355 aa of NM_010555.4 Sequence: FTTPTVVHTGKVSESPITSEKPTVHGDNCQFRGREFKSELRLEGEPVVLRCPLAPHSDISSSSHSFLTWSKLDSSQLIPRDEPRMWVKGNILWILPAVQQDSGTYICTFRNASHCEQMSVELKVFKNTEASLPHVSYLQISALSTTGLLVCPDLKEFISSNADGKIQWYKGAILLDKGNKEFLSAGDPTRLLISNTSMDDAGYYRCVMTFTYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWLANSTFISAAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTREDLHTDFKCVASNPRSSQSLHTTVKE Predict reactive species
Full Name: interleukin 1 receptor, type II
Calculated Molecular Weight: 46 kDa
GenBank Accession Number: NM_010555.4
Gene Symbol: Il1r2
Gene ID (NCBI): 16178
Conjugate: APC Fluorescent Dye
Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P27931
Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
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Collaboration
Tony Tang
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