Proteintech, Biotin-FcA65657, FcZero-rAb™ Biotin Anti-Mouse CD134/OX40 (OX-86) Rabbit Recombinant Antibody

Size: 100ug The CD134/OX40 (Biotin-FcA65657) by Proteintech is a Recombinant antibody targeting CD134/OX40 in FC, ELISA applications with reactivity to mouse samples Biotin-FcA65657 targets CD134/OX40 in FC, ELISA applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: Anti-CD3/CD28 treated mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: tumor necrosis factor receptor superfamily, member 4 GenBank Accession Number: BC065782 Gene Symbol: CD134 Gene ID (NCBI): 22163 Conjugate: Biotin Excitation/Emission Maxima Wavelengths: - Form: Liquid Purification Method: Protein A purification UNIPROT ID: P47741 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.