Proteintech, Biotin-FcA65671, FcZero-rAb™ Biotin Anti-Mouse CD18 (M18/2) Rabbit IgG Recombinant Antibody

Size: 100ug The CD18 (Biotin-FcA65671) by Proteintech is a Recombinant antibody targeting CD18 in FC, ELISA applications with reactivity to mouse samples Biotin-FcA65671 targets CD18 in FC, ELISA applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse thymocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: integrin beta 2 GenBank Accession Number: BC145644 Gene Symbol: CD18 Gene ID (NCBI): 16414 Conjugate: Biotin Excitation/Emission Maxima Wavelengths: - Form: Liquid Purification Method: Protein A purification UNIPROT ID: P11835 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.