Proteintech, Biotin-FcA98221, FcZero-rAb™ Biotin Anti-Human CCL20/MIP-3 alpha Rabbit Recombinant Antibody

Size: 100ug The CCL20/MIP-3 alpha (Biotin-FcA98221) by Proteintech is a Recombinant antibody targeting CCL20/MIP-3 alpha in FC (Intra), ELISA applications with reactivity to human samples Biotin-FcA98221 targets CCL20/MIP-3 alpha in FC (Intra), ELISA applications and shows reactivity with human samples. Tested Applications Positive FC (Intra) detected in: PMA, LPS and Brefeldin A treated THP-1 cells Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2398 Product name: Recombinant Human CCL20/MIP-3 alpha protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 27-96 aa of NM_004591.3 Sequence: ASNFDCCLGYTDRILHPKFIVGFTRQLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVRLLSKKVKNM Predict reactive species Full Name: chemokine (C-C motif) ligand 20 Calculated Molecular Weight: 11kDa GenBank Accession Number: NM_004591.3 Gene Symbol: CCL20/MIP-3 alpha Gene ID (NCBI): 6364 Conjugate: Biotin Excitation/Emission Maxima Wavelengths: - Form: Liquid Purification Method: Protein A purification UNIPROT ID: P78556-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.