Proteintech, CL555-ctl, ChromoTek anti-CTLA4 recombinant VHH, CoraLite® Plus 555

Size: 150ul CL555-ctla targets CTLA4 in FC and IF applications and shows reactivity with Human samples. Specification Applications: FC, IF Reactivity: Human Conjugate: CoraLite® Plus 555 Type: Nanobody Class: Recombinant Host: Alpaca Affinity: 22 nM Molecular Weight: 14.005 kDa Form: Liquid Excitation/Emission Maxima Wavelengths: 554 nm / 570 nm RRID: AB_3101938 Storage Buffer: 500 mM NaCl, 10 mM HEPES pH 7.0, 5 mM EDTA, 0.09% sodium azide Storage Condition: Store at -20°C Background: CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses. Besides the full-length transmembrane form, CTLA-4 also exists in a truncated soluble form (sCTLA-4).