Product Description
Size: 100ul
The DDX18 (CL594-85789-2) by Proteintech is a Recombinant antibody targeting DDX18 in IF/ICC applications with reactivity to human samples
CL594-85789-2 targets DDX18 in IF/ICC applications and shows reactivity with human samples.
Tested Applications
Positive IF/ICC detected in: HepG2 cells
Recommended dilution
Immunofluorescence (IF)/ICC: IF/ICC : 1:500-1:2000
Background Information
DDX18 (DEAD-box helicase 18) is a protein belonging to the DEAD-box deconjugating enzyme family that is widely involved in RNA metabolism. It plays a key role in the assembly of the ribosomal small subunit (SSU) and ensures efficient intracellular protein synthesis. DDX18 unwinds RNA double strands through its deconjugating enzyme activity, which is essential for the proper processing and functional execution of RNA molecules. In addition, DDX18 is a multifunctional RNA deconjugating enzyme involved in a variety of signaling pathways, playing a key role not only in ribosome assembly and RNA metabolism, but also in the regulation of a variety of biological processes such as cell cycle, genome stability and stem cell pluripotency.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag27457 Product name: Recombinant human DDX18 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 7-165 aa of BC001238 Sequence: KLLRKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKPMNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPS Predict reactive species
Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Calculated Molecular Weight: 75 kDa
Observed Molecular Weight: 80 kDa
GenBank Accession Number: BC001238
Gene Symbol: DDX18
Gene ID (NCBI): 8886
Conjugate: CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths: 588 nm / 604 nm
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q9NVP1
Storage Buffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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