Proteintech, KE10012, Mouse IL-21 ELISA Kit

Size: 96t / 5*96t / 10*96t Background Information Interleukin 21 (IL-21) is a cytokine produced predominantly by cluster of differentiation 4 (CD4+) T-cells and natural killer T-cells. IL-21 is preliminarily expressed in activated cluster of differentiation 4 (CD4+) T-cells and natural killer (NK) T-cells. IL-21 receptor (il21R) is a class I cytokine receptor, which requires dimerization with the indispensable common gamma chain (γc) subunit to bind IL-21. IL-21 plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. IL-21 mediates apoptosis in B-CLL cells through up-regulation of the BIM (BH3 family member) and enhances both direct and antibody-dependent cellular cytotoxicity in these cells. Specification Product name: Mouse IL-21 ELISA Kit Tests: 1 X 96 well plate Sample type: Serum, Plasma, Cell culture supernatants Assay type: Sandwich Sensitivity: 0.5 pg/mL Range: 15.6-1000 pg/mL Reactivity: Mouse Tested applications: Sandwich ELISA Gene ID (NCBI): 60505 Mouse serum: 92% Cell culture supernatants: 76% 1: 20 2: 20 3: 20 1: 24 2: 24 3: 24 Storage Instructions: All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms: Il21, IL-21, interleukin 21, Interleukin-21