Product Description
Size: 100ug
The CD4 (SF98042-1-RR) by Proteintech is a Recombinant antibody targeting CD4 in FC applications with reactivity to human, monkey, non-human primates samples
SF98042-1-RR targets CD4 in FC applications and shows reactivity with human, monkey, non-human primates samples.
Tested Applications
Positive FC detected in: human PBMCs
Recommended dilution
Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
CD4 is a 55-kDa transmembrane glycoprotein expressed on T helper cells, the majority of thymocytes, monocytes, macrophages, and dendritic cells (PMID: 9304802; 12213222). CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It plays an important role in T helper cell development and activation (PMID: 9539765; 3112582). CD4 serves as a receptor for the human immunodeficiency virus (HIV) (PMID: 9304802).
Specification
Tested Reactivity: human, monkey, non-human primates
Host / Type: Rabbit / scFv
Class: Recombinant
Type: Single-chain variable fragment antibody (scFv)
Immunogen: CatNo: Eg0333 Product name: Recombinant Human CD4 protein (His Tag) Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 26-396 aa of BC025782 Sequence: KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQP Predict reactive species
Full Name: CD4 molecule
Calculated Molecular Weight: 55 kDa
GenBank Accession Number: BC025782
Gene Symbol: CD4
Gene ID (NCBI): 920
ENSEMBL Gene ID: ENSG00000010610
Conjugate: Unconjugated
Source: Anti-Human CD4 scFv from clone 240427E12, consisting of VH-GGGGS linker-VL (N- to C-terminus), with a His-C tag at the C-terminus.
Form: Liquid
Purification Method: Protein A purification
Storage Buffer: 50mM HEPES, 150mM NaCl, 5mM EDTA, 0.1% CHAPS, 10% Sucrose and 0.1% Proclin 300, pH 7.3.
Storage Conditions: Store at 2-8°C. Stable for one year after shipment. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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