Revvity, 62AMXADA, HTRF IBMX Phosphodiesterase Inhibitor, 40 µL

Overview
PDEs are represented by a large super-family of enzymes whose role is to hydrolyze cAMP into AMP, and cGMP into GMP. It should be emphasized that while not all PDEs lead to the specific hydrolysis of cAMP, the non-selective PDE inhibitor IBMX is often the preferred chemical used in most cAMP accumulation assays.
The use of a Pan-PDE inhibitor ensures that the hydrolysis effect of most PDEs will be inhibited, which in turn guarantees high levels of cAMP accumulation in the cell.
HTRF assays offer many advantages over other technologies:

Homogeneous add-and-read format
No wash steps
Low background
Straightforward miniaturization from 96- or 384-well microplates to high density assay formats such as 384-well low volume and 1536-well plates
Stable signal, providing flexibility in time of readout or size of assays Application-Second Messenger Detection
Brand-HTRF
Detection Modality-HTRF
Product Group-Buffer
Shipping Conditions-Shipped Ambient
Target Class-GPCR
Technology-TR-FRET
Therapeutic Area-Cardiovascular Infectious Diseases Metabolism/Diabetes NASH/Fibrosis Neuroscience Oncology & Inflammation Rare Diseases
Unit Size-40 assay points