Revvity, 81MOIGG1NC, pHSense Mouse IgG1 Negative Control, 50µg

Overview
pHSense Eu Fab reagents are designed to monitor antibody or anti-drug conjugate (ADC), as well as receptor- and membrane protein-mediated internalization in real time. To confidently attribute observed effects to specific antigen binding, it is crucial to include proper controls. Test antibodies may engage in non-specific interactions - particularly when their Fc regions bind to Fc receptors on cells - which can contribute to background signal. This is where negative control antibodies become essential in pHSense assays. They help distinguish true signal from background noise by revealing non-specific binding effects, thereby enhancing the reliability of your internalization measurements.
The pHSense Mouse IgG1 Negative Control is a purified mouse IgG1 antibody. It serves as an ideal isotype control when evaluating mouse IgG1 antibodies in conjunction with pHSense reagents. Application-Internalization
Brand-pHSense
Detection Modality-pH sensitive dye
Product Group-Fluorescent Reagent
Shipping Conditions-Shipped in Dry Ice
Target Class-ADCs Antibodies Cell surface proteins GPCRs
Target Species-Mouse
Technology-TRF
Unit Size-1 vial