Product Description
Overview
The GIP receptor is a member of the Class B GPCR family. GIPR is activated by Gastric Inhibitory Polypeptide (GIP) known as glucose-dependent insulinotropic polypeptide. GIP has numerous physiologic actions, including stimulation of glucagon and insulin release by pancreatic islet cells.
This HEK293 stable cell line expresses the GIP receptor fused to a SNAP-Tag. Labeled with Terbium, the cells can be used in a Tag-lite receptor binding protocol.
Tag-lite assays offer many features and applications over traditional receptor/ligand binding assays:
Non-radioactive
Homogeneous and filtration-free
Ready-to-use kits and reagents for binding assays
Does not alter the receptor pharmacology
Peer-reviewed, validated technology
Thorough kinetic studies with true Kd and Ki values, association (Kon) and dissociation (Koff) rate constants
Screening and profiling of biologics and large molecules Application-Receptor-Ligand Binding
Brand-Tag-lite
Detection Modality-HTRF
Product Group-Cells
Shipping Conditions-Shipped in Dry Ice
Target Class-GPCR
Target Species-Human
Technology-TR-FRET
Therapeutic Area-Cardiovascular Central Nervous System Infectious Diseases Inflammation Metabolism/Diabetes NASH/Fibrosis Oncology Rare Diseases
Unit Size-1 each
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924