Revvity, NEC160250UC, Citric Acid, [1,5- C]-, EtOH Sol, 250 µCi (9.25 MBq)

Overview
ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity. Concentration-0.05 mCi/mL
Molecular Weight-192.12
Specific Activity-100 - 124 mCi/mmol (3700 - 4588 MBq/mmol)
CAS Number-77-92-9
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Ethanol : water (2:98)
Detection Modality-Radiometric
Label Position-Specifically Labeled
Molecular Formula-C6H8O7
Packaging-NENSure vial
Radioisotope-14 C
Shipping Information-Blue Ice
Shipping Conditions-Shipped in Blue Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions-5°C
Unit Size-250 µCi